![]() Some causes of Nocturia are polyuria, nocturnal polyuria, bladder storage. A multidisciplinary approach is necessary to effectively diagnose and manage this bothersome condition.Ĭopyright © 2019. Nocturia is when you wake up more than one time each night to go to the bathroom. Overall, the pathophysiology of NP is complex and differs from that of other types of nocturia. Desmopressin, a synthetic analog of arginine vasopressin, is the only antidiuretic treatment indicated specifically for nocturia due to NP. Antidiuretic treatment is warranted for patients with nocturia due to NP because, in many patients, it treats the underlying cause (ie, insufficient secretion of antidiuretic hormone arginine vasopressin) that leads to overproduction of urine at night and has been shown to provide statistically significant reductions in nocturnal voids. While drugs for benign prostatic hyperplasia and overactive bladder have demonstrated statistically significant reductions in nocturnal voids, patients often fail to achieve a clinically meaningful response. ![]() Lifestyle modifications are the first intervention implemented for the management of nocturia and NP but, as symptoms progress, such measures may be insufficient, and pharmacotherapy may be initiated. Diagnostic tools, in addition to a thorough history and physical examination, include voiding/bladder diary analyses and questionnaires to diagnose nocturia type (NP, diminished nocturnal/global bladder capacity, global polyuria) and causative factors. Causes See a doctor Prevention Treatments Alternative treatments Takeaway Overactive bladder at night If you need to get up to urinate more than one time during the night, you may have an. It is therefore important to accurately diagnose both the type of nocturia and the potentially associated medical conditions to determine appropriate treatment. Nocturnal polyuria exists when the nocturnal urine volume represents >20 of the 24 hour voided volume in younger adults and >33 in patients aged 65 years and over. Nocturia can be caused by intake, urological, nephrological, hormonal, sleep, and cardiovascular factors. International Journal of Urology.Nocturnal polyuria (NP), characterized by overproduction of urine at night (greater than 20%-33% of total 24-hour urine volume depending on age), is a major contributing factor in most nocturia cases. International Journal of Clinical Practice. Nocturia: Risk factors and associated comorbidities Findings from the EpiLUTS study.
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